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The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients

Received: 23 December 2020     Accepted: 7 January 2021     Published: 25 January 2021
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Abstract

Background: The lower number of platelet (PLT) has been found to be a risk factor in patients with type A acute aortic dissection (AAD) In admission. However prognostic implications of the PLT count in the type B AAD patients has not yet been elucidated. Methods: We consecutively enrolled 81 patients which confirmed with type B. Patients were divided into survival group and death group and PLT count were measured on admission. Univariate analysis and multiple logistic regression analysis were used to identify the predictors of in-hospital mortality. Results: Compared with the survival group, the death group PLT count was significant lower (172.07±57.38×109/L vs. 227.13±75.97×109/L, P<0.05). The results showed PLT count (HR: 0.993, 95% CI: 0.987-0.997, P=0.043), the area under the ROC curve of PLT count was 0.717, the best cut off was 179.5 × 109 / L, the sensitivity was 72.5%, the specificity was 63.3%, P=0.001; Log Rang test results showed that there was a statistically significant difference in cumulative survival between the high PLT count group (>179.5 × 109 / L) and the low PLT count group (<179.5 × 109 / L) (P=0.001). Conclusions: Low PLT on admission count is one of the specific dead risk factors for type B AAD in-hospital patients.

Published in International Journal of Biomedical Science and Engineering (Volume 9, Issue 1)
DOI 10.11648/j.ijbse.20210901.12
Page(s) 6-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Platelet Count, Acute Aortic Dissection, Stanford Type B

References
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  • APA Style

    Wenming Shao, Zengxi Yao, Yabin Jiang. (2021). The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients. International Journal of Biomedical Science and Engineering, 9(1), 6-10. https://doi.org/10.11648/j.ijbse.20210901.12

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    ACS Style

    Wenming Shao; Zengxi Yao; Yabin Jiang. The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients. Int. J. Biomed. Sci. Eng. 2021, 9(1), 6-10. doi: 10.11648/j.ijbse.20210901.12

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    AMA Style

    Wenming Shao, Zengxi Yao, Yabin Jiang. The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients. Int J Biomed Sci Eng. 2021;9(1):6-10. doi: 10.11648/j.ijbse.20210901.12

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  • @article{10.11648/j.ijbse.20210901.12,
      author = {Wenming Shao and Zengxi Yao and Yabin Jiang},
      title = {The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients},
      journal = {International Journal of Biomedical Science and Engineering},
      volume = {9},
      number = {1},
      pages = {6-10},
      doi = {10.11648/j.ijbse.20210901.12},
      url = {https://doi.org/10.11648/j.ijbse.20210901.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20210901.12},
      abstract = {Background: The lower number of platelet (PLT) has been found to be a risk factor in patients with type A acute aortic dissection (AAD) In admission. However prognostic implications of the PLT count in the type B AAD patients has not yet been elucidated. Methods: We consecutively enrolled 81 patients which confirmed with type B. Patients were divided into survival group and death group and PLT count were measured on admission. Univariate analysis and multiple logistic regression analysis were used to identify the predictors of in-hospital mortality. Results: Compared with the survival group, the death group PLT count was significant lower (172.07±57.38×109/L vs. 227.13±75.97×109/L, P9 / L, the sensitivity was 72.5%, the specificity was 63.3%, P=0.001; Log Rang test results showed that there was a statistically significant difference in cumulative survival between the high PLT count group (>179.5 × 109 / L) and the low PLT count group (9 / L) (P=0.001). Conclusions: Low PLT on admission count is one of the specific dead risk factors for type B AAD in-hospital patients.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - The Significance of Platelet Count in Short-Term Prognosis of Type B Acute Aortic Dissection Patients
    AU  - Wenming Shao
    AU  - Zengxi Yao
    AU  - Yabin Jiang
    Y1  - 2021/01/25
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijbse.20210901.12
    DO  - 10.11648/j.ijbse.20210901.12
    T2  - International Journal of Biomedical Science and Engineering
    JF  - International Journal of Biomedical Science and Engineering
    JO  - International Journal of Biomedical Science and Engineering
    SP  - 6
    EP  - 10
    PB  - Science Publishing Group
    SN  - 2376-7235
    UR  - https://doi.org/10.11648/j.ijbse.20210901.12
    AB  - Background: The lower number of platelet (PLT) has been found to be a risk factor in patients with type A acute aortic dissection (AAD) In admission. However prognostic implications of the PLT count in the type B AAD patients has not yet been elucidated. Methods: We consecutively enrolled 81 patients which confirmed with type B. Patients were divided into survival group and death group and PLT count were measured on admission. Univariate analysis and multiple logistic regression analysis were used to identify the predictors of in-hospital mortality. Results: Compared with the survival group, the death group PLT count was significant lower (172.07±57.38×109/L vs. 227.13±75.97×109/L, P9 / L, the sensitivity was 72.5%, the specificity was 63.3%, P=0.001; Log Rang test results showed that there was a statistically significant difference in cumulative survival between the high PLT count group (>179.5 × 109 / L) and the low PLT count group (9 / L) (P=0.001). Conclusions: Low PLT on admission count is one of the specific dead risk factors for type B AAD in-hospital patients.
    VL  - 9
    IS  - 1
    ER  - 

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Author Information
  • Department Emergency, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department Emergency, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department Emergency, The First Affiliated Hospital of Jinan University, Guangzhou, China

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