Research Article
Quantitative Evaluation and Comparative Analysis of Toxic Heavy Metal Levels (Pb and Mn) in Pineapple, Papaya, Banana and Mango Fruit Purchased from Tepi Market
Desalegn Tesfa Tefera*
Issue:
Volume 12, Issue 2, June 2024
Pages:
13-23
Received:
10 June 2024
Accepted:
1 July 2024
Published:
23 July 2024
Abstract: This study aimed to analyze the composition and safety of commonly consumed fruits, namely pineapples, papaya, banana, and mango, and evaluate their suitability as part of a balanced diet. The fruits were assessed for moisture content, ash content, and heavy metal concentrations, specifically lead (Pb) and manganese (Mn). The moisture content values obtained for pineapple (81.3% ± 0.8), papaya (75.8% ± 1), banana (76% ± 0.5), and mango (83.8% ± 1) indicate varying levels of water content in these fruits. In terms of ash content, the values measured for pineapple (0.66% ± 1), papaya (1% ± 0.5), banana (1.6% ± 1), and mango (2.3% ± 1) indicate the ash content present in these fruits. The concentrations of lead and manganese in the fruit samples were within acceptable ranges, with values for lead ranging from 0.04 ppm to 0.08 ppm, and values for manganese ranging from 0.002 ppm to 0.006 ppm. These results assure the safety of these fruits for consumption. However, further research is recommended to explore factors affecting fruit composition, such as varietal differences and environmental conditions. These findings emphasize the importance of sourcing fruits from reputable suppliers and practicing proper fruit handling and storage. Overall, including these fruits in a balanced diet provides essential nutrients and contributes to a healthy lifestyle. Continuous monitoring and research are crucial to ensure the quality and safety of these fruits for long-term consumption.
Abstract: This study aimed to analyze the composition and safety of commonly consumed fruits, namely pineapples, papaya, banana, and mango, and evaluate their suitability as part of a balanced diet. The fruits were assessed for moisture content, ash content, and heavy metal concentrations, specifically lead (Pb) and manganese (Mn). The moisture content value...
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Research Article
A Novel Analytical Method for Determining a Combination of Tetrahydrozoline and Antazoline HCl by Modulating Ratio Spectra
Issue:
Volume 12, Issue 2, June 2024
Pages:
24-32
Received:
8 August 2024
Accepted:
2 September 2024
Published:
26 September 2024
Abstract: In this study, the combination of pharmaceutical formulation of tetrahydrozline HCl (TZ) and antazoline HCl (AN) was determined without separating them using smart analytical UV spectrophotometric methods. While the Extended Ratio Subtraction Method (EXRSM) is used to determine AN, the Ratio Subtraction Method (RSM) is utilized to determine TZ and is linked with the ratio subtraction technique. The calibration curves for AN and TZ are linear, ranging from 3.0 to 30.0 µg/mL and 5.0 to 45.0 µg/mL, respectively. Analyzing several laboratory-prepared combinations of the two medications allowed researchers to assess the specificity of the designed methods. The selected drugs' combined dosage form was determined with success using both approaches. Validation was carried out in accordance with ICH requirements, and it was found that repeatability, accuracy, and intermediate precision were all within acceptable limits. Statistical studies showed that both methods can be competitively applied in quality control laboratories. RSM and the EXRSM are complementary to one another, as shown by the determination of AN and TZ without pre-separation. Without any prior separation, the EXRSM was able to differentiate between substances with an extended spectrum using the same characteristics. Therefore, one alternative approach to liquid chromatography techniques is the combination of EXRSM and RSM.
Abstract: In this study, the combination of pharmaceutical formulation of tetrahydrozline HCl (TZ) and antazoline HCl (AN) was determined without separating them using smart analytical UV spectrophotometric methods. While the Extended Ratio Subtraction Method (EXRSM) is used to determine AN, the Ratio Subtraction Method (RSM) is utilized to determine TZ and ...
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